Methods of increasing or decreasing carotenoids and other isoprenoids using IPP isomerase
US6524811B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Sep 25, 1997 |
| Grant date | Feb 25, 2003 |
| Priority date | — |
| Expiry date | Sep 25, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P23/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention describes the DNA sequence for eukaryotic genes encoding &egr; cyclase, isopentenyl pyrophosphate (IPP) isomerase and &bgr;-carotene hydroxylase as well as vectors containing the same and host cells transformed with said vectors. The &egr; cyclase and &bgr;-carotene hydroxylase genes disclosed include those from A. thaliana; the IPP isomerase genes disclosed include those from A. thaliana, H. pluvialis, and marigold. The present invention also provides methods for controlling the ratio of various carotenoids in a host cell and for the production of novel carotenoid pigments. The present invention also provides a method for screening for eukaryotic genes encoding carotenoid biosynthesis enzymes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.