Recombinant megalomicin biosynthetic genes and uses thereof
US6524841B1 · kind B1 · utility
8Cited by
8References
7Claims
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Key dates
| Filing date | Oct 4, 2000 |
| Grant date | Feb 25, 2003 |
| Priority date | — |
| Expiry date | Oct 4, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Recombinant nucleic acids that encode all or a portion of the megAI gene of the megalomicin polyketide synthase (PKS) of Micromonospora megalomicea are used to produce recombinant PKS enzymes in host cells to make megalomicin, megalomicin derivatives, and other polyketides that are useful as antibiotics, motilides, and antiparasitics.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.