Manganese or iron complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide
US6525041B1 · kind B1 · utility
29Cited by
8References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 14, 1996 |
| Grant date | Feb 25, 2003 |
| Priority date | — |
| Expiry date | Mar 14, 2016 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S977/915
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Low molecular weight mimics of superoxide dismutase (SOD) represented by the formula: wherein R, R′, R1, R′1, R2, R′2, R3, R′3, R4, R′4, R5, R′5, R6, R′6, R7, R′7, R8, R′8, R9, and R′9, M, X, Y, Z and n are as defined herein, useful as therapeutic agents for inflammatory disease states and disorders, ischemic/reperfusion injury, stroke, atherosclerosis, and all other conditions of oxidant-induced tissue damage or injury.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.