Polylactide/dextran graft co-polymers for biomaterial and tissue engineering applications
US6525145B2 · kind B2 · utility
48Cited by
3References
14Claims
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Key dates
| Filing date | May 31, 2001 |
| Grant date | Feb 25, 2003 |
| Priority date | — |
| Expiry date | Jul 21, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2300/602
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A biocompatible, biodegradable, copolymer is prepared from cross-linking a polylactic acid with a polysaccharide such as dextran. The resulting copolymer is a biodegradable hydrogel or solid having both hydrophobic and hydrophilic properties and provides for a mechanism in which biologically active agents may be covalently bonded to the dextran prior to incorporation of the dextran into a copolymer, and the subsequent release of the biologically active agents as the copolymer degrades.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.