Truncated forms of NY-ESO-1 protein

US6525177B2 · kind B2 · utility

Assignees

• Cornell Research Foundation, Inc. · US
• LUDWIG INSTITUTE FOR CANCER RESEARCH LTD · GB
• SLOAN KETTERING CANCER CENTER · US

Inventors

• Elisabeth Stockert · New York, US
• Elke Jager · Frankfurt am Main, DE
• Yao-Tseng Chen · New York, US
• Matthew Scanlan · Princeton Junction, US
• Knuth Alexander · Frankfurt am Main, DE
• Lloyd J. Old · New York, US

Key dates

• Filing date: Dec 29, 2000
• Grant date: Feb 25, 2003
• Expiry date: Mar 3, 2021

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K39/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to antibodies which bind to the cancer associated antigen NY-ESO-1. Both polyclonal and monoclonal antibodies are part of the invention, as are chimeric forms of the antibodies, and binding portions of antibodies. Uses of these antibodies are described. Also described are truncated, recombinant forms of the cancer associated antigen.