Patent · US Expired

Imidazoloisoquinolines

US6528649B2 · kind B2 · utility

2Cited by
2References
26Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 29, 2001
Grant dateMar 4, 2003
Priority date
Expiry dateMay 29, 2021

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D487/04
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Disclosed are compounds of the formula: and the pharmaceutically acceptable salts, prodrugs and solvates thereof, wherein n, R1, R2, R3, W, Q, and X are defined herein, which compounds bind with high selectivity and high affinity to the benzodiazepine site of the GABAA receptors and are therefore useful in the treatment of certain central nervous system (CNS) diseases and as probes for the localization of GABAA receptors in tissue samples.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.