Methods to identify compounds that affect the expression level of the syntaxin-1 A encoding gene
US6531288B1 · kind B1 · utility
2Cited by
2References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 13, 2000 |
| Grant date | Mar 11, 2003 |
| Priority date | — |
| Expiry date | Oct 13, 2020 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/04
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A specific amino acid sequence proximal to the carboxy terminus of P/Q type ion channels has been shown to mediate, through binding to the Homer protein, the expression of the gene encoding syntaxin-1A. This region of the P/Q type calcium ion channel provides peptides that can be used in screening assays for compounds that modulate the central nervous system.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.