Tricyclic carbapenem compounds

US6531466B2 · kind B2 · utility

Assignee

• GLAXOSMITHKLINE SA · IT

Inventors

• Tino Rossi · Verona, IT
• Daniele Andreotti · Verona, IT
• Giovanna Tedesco · Verona, IT
• Luca Tarsi · Verona, IT
• Emiliangelo Ratti · Verona, IT
• Aldo Feriani · Verona, IT
• Domenica Antonia Pizzi · Verona, IT
• Giovanni Gaviraghi · Verona, IT
• Stefano Biondi · Verona, IT
• Gabriella Finizia · Verona, IT

Key dates

• Filing date: Feb 13, 2001
• Grant date: Mar 11, 2003
• Expiry date: Feb 13, 2021

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D477/00
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A compound of formula (I), salts and metabolically labile esters thereof, wherein R represents optionally substituted aryl or heteroaryl group; A represents a propylene chain or A is a chain of 3 members one of which is selected from an oxygen or sulphur atom or the group NH or a substituted derivative thereof and the other two members are methylene groups, having antibacterial activity, processes for their preparation and to their use in medicine.