CRF receptor antagonists and methods relating thereto
US6531475B1 · kind B1 · utility
18Cited by
5References
44Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 18, 2000 |
| Grant date | Mar 11, 2003 |
| Priority date | — |
| Expiry date | May 18, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/16
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
CRF receptor antagonists are disclosed which have utility in the treatment of a variety of disorders, including the treatment of disorders manifesting hypersecretion of CRF in a warm-blooded animals, such as stroke. The CRF receptor antagonists of this invention have the following structure: including stereoisomers and pharmaceutically acceptable salts thereof, wherein n, m, A, B, C, R, R1, R2 and Ar are as defined herein. Compositions containing a CRF receptor antagonist in combination with a pharmaceutically acceptable carrier are also disclosed, as well as methods for use of the same
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.