Various thiol complexes, processes for their synthesis and clinical applications
US6531608B2 · kind B2 · utility
4Cited by
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20Claims
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Assignee
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Key dates
| Filing date | Jun 11, 2002 |
| Grant date | Mar 11, 2003 |
| Priority date | — |
| Expiry date | Jun 11, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/555
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to the synthesis of certain complexes of cysteine, N-acetylcysteine, N-(2-mercaptopropionyl)glycine, and L-2-oxothiazolidine-4-carboxylate and to the nutritional use of these and other related individual or complexed thiol-contributing glutathione predecessors. Clinical uses for these molecules and complexes in the beneficial modification of various physiological conditions and functions associated with aging, chronic glaucoma, diabetes mellitus, insulin resistance, macular degeneration, neurodegenerative diseases and vasoconstriction are described in particular.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.