Protected one-vial formulation for nucleic acid molecules, methods of making the same by in-line mixing, and related products and methods
US6534483B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 10, 1999 |
| Grant date | Mar 18, 2003 |
| Priority date | — |
| Expiry date | Aug 10, 2019 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S977/907
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention, as noted above, relates generally to the incorporation of plasmid into a conventional dosage form, and more particularly to the production of a single-vial, homogenized, plasmid/polymer complex with desirable physical characteristics. Methods of making, storing and using such a complex are also provided and described in detail below. Such products and methods will provide more convenient and cost-effective complexes, which will be protected against chemical degradation and/or physical aggregation of its components and will provide for relative ease of administration. Thus, the present invention provides a more efficient complex for plasmid delivery and a method of incorporation of that plasmid into a conventional dosage form.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.