Patent · US Expired

Therapeutic polymorphs of a GABA-A alpha-5 inverse agonist and pamoate formulations of the same

US6534505B2 · kind B2 · utility

2Cited by
3References
8Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 30, 2000
Grant dateMar 18, 2003
Priority date
Expiry dateJan 6, 2021

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P25/28
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

There is disclosed 3-(5-methylisoxazol-3-yl)-6-(1-methyl-1,2,3-triazol-4-yl)methyloxy-1,2,4-triazolo[3,4-a]phthalazine in the form of a dihydrate, a dehydrate of the dihydrate and a pentahydrate, pharmaceutical compositions comprising the forms, the use of the forms for enhancing cognition, processes for producing the forms, their incorporation in pharmaceutical compositions comprising pamoate ions and the use of such ions for solubilizing neutral molecules.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.