Controlled release formulations
US6534549B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 1, 2000 |
| Grant date | Mar 18, 2003 |
| Priority date | — |
| Expiry date | Mar 1, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P1/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for producing a controlled release composition is provided. A solution of a film-forming composition comprising a mixture of a substantially water-insoluble film-forming polymer and amylose in a solvent system comprising (1) water and (2) a water-miscible organic solvent which on its own is capable of dissolving the film-forming polymer is contacted with an active material and the resulting composition dried. The weight ratio of amylose to film-forming insoluble polymer in the film-forming composition is in the range 1:2 to 3:2 and the organic solvent comprises at least 50% by weight of the solvent system. The composition is particularly suitable for delivering therapeutic agents to the colon.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.