Nematode-extracted serine protease inhibitors and anticoagulant proteins
US6534629B1 · kind B1 · utility
1Cited by
31References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 12, 1999 |
| Grant date | Mar 18, 2003 |
| Priority date | — |
| Expiry date | Feb 12, 2019 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/829
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Proteins which have activity as anticoagulants and/or serine protease inhibitors and have at least one NAP domain and are described. Certain of these proteins have factor Xa inhibitory activity and others have activity as inhibitors of factor VIIa/TF. These proteins can be isolated from natural sources as nematodes, chemically synthesized or made by recombinant methods using various DNA expression systems.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.