Compositions and methods for the treatment and diagnosis of cardiovascular disease
US6534641B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Mar 28, 1997 |
| Grant date | Mar 18, 2003 |
| Priority date | — |
| Expiry date | Mar 28, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/15
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to methods and compositions for the treatment and diagnosis of cardiovascular disease, including, but not limited to, atherosclerosis, ischemia/reperfusion, hypertension, restenosis, and arterial inflammation. Specifically, the present invention identifies and describes genes which are differentially expressed in cardiovascular disease states, relative to their expression in normal, or non-cardiovascular disease states, and/or in response to manipulations relevant to cardiovascular disease. Further, the present invention identifies and describes genes via the ability of their gene products to interact with gene products involved in cardiovascular disease. Still further, the present invention provides methods for the identification and therapeutic use of compounds as treatments of cardiovascular disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.