Method for the analysis of abnormal particle populations
US6535836B1 · kind B1 · utility
Assignee
Inventor
Key dates
| Filing date | Sep 29, 2000 |
| Grant date | Mar 18, 2003 |
| Priority date | — |
| Expiry date | Feb 15, 2021 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2015/1488
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method for analyzing an abnormal particle population in an experimental sample containing particles involves a particle property distribution index based on an average particle property (e.g., size) distribution curve for multiple normal samples in a particle analysis instrument. The process involves producing an experimental particle property distribution curve by analyzing an experimental sample containing particles in the instrument. The distribution curve of the experimental sample is analyzed to identify particle populations at the lower or upper region of the experimental distribution curve that differ from particle populations in the regions of an average particle property distribution curve. Thereafter, the number of particles within the lower or upper region of the experimental distribution curve that differs from the average curve is determined and employed for diagnosis of a relevant characteristic of the particle population. A computer program which makes calculations for such methods can be employed or can be integrated into a particle analysis instrument. The method, program, and instruments of this invention provide a novel red blood cell parameter.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.