Amino-terminal modified parathyroid hormone (PTH) analogs
US6537965B1 · kind B1 · utility
18Cited by
4References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 23, 1999 |
| Grant date | Mar 25, 2003 |
| Priority date | — |
| Expiry date | Nov 23, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are novel parathyroid hormone (PTH) peptide derivatives. In particular, the invention relates to PTH derivatives having amino acid substitutions that confer PTH-1/PTH-2 receptor agonist or antagonist properties to the derivatives. Also disclosed are methods of preparing these novel derivatives, and methods of using these derivatives to treat mammalian conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.