Gonadotropin-releasing hormone receptor antagonists and methods relating thereto
US6537998B1 · kind B1 · utility
0Cited by
2References
30Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 16, 2000 |
| Grant date | Mar 25, 2003 |
| Priority date | — |
| Expiry date | Oct 16, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P5/02
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
GnRH receptor antagonists are disclosed which have utility in the treatment of a variety of sex-hormone related conditions in both men and women. The compounds of this invention have the structure: wherein Ar, A, B, Q, R1, R2, R3a, R3b, R6, R7 and m are as defined herein, including stereoisomers, prodrugs and pharmaceutical acceptable salts thereof. Also disclosed are compositions containing a compound of this invention in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for antagonizing gonadotropin-releasing hormone in a subject in need thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.