Method for inhibiting complement activation
US6538028B1 · kind B1 · utility
Assignees
Inventors
Key dates
| Filing date | Feb 1, 2001 |
| Grant date | Mar 25, 2003 |
| Priority date | — |
| Expiry date | Feb 1, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K16/2896
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of inhibiting complement activation, particularly by a transplanted tissue, in a warm-blooded vertebrate. The method includes administering a therapeutically effective amount of a platelet activity modulator to a warm-blooded vertebrate before, during or after a tissue is transplanted to the warm-blooded vertebrate, whereby complement activation by the transplanted tissue is inhibited. The platelet activity modulator can include a combination of a GPIb modulator and a GPIIb/GPIIIa modulator.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.