Expression of lipoproteins
US6538118B1 · kind B1 · utility
8Cited by
28References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 28, 1998 |
| Grant date | Mar 25, 2003 |
| Priority date | — |
| Expiry date | Apr 28, 2018 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Heterologous lipidated proteins formed recombinantly are disclosed and claimed. The expression system can be E. coli. The heterologous lipidated protein has a leader sequence which does not naturally occur with the protein portion of the lipidated protein. The lipidated protein can have the Borrelia OspA leader sequence. The protein portion can be OspC, PspA, UreA, Ure B, or a fragment thereof. Methods and compositions for forming and employing the proteins are also disclosed and claimed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.