Anti-viral vectors
US6541248B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 20, 2000 |
| Grant date | Apr 1, 2003 |
| Priority date | — |
| Expiry date | Apr 20, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/16043
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A viral vector production system is provided which system comprises:(i) a viral genome comprising at least one first nucleotide sequence encoding a gene product capable of binding to and effecting the cleavage, directly or indirectly, of a second nucleotide sequence, or transcription product thereof, encoding a viral polypeptide required for the assembly of viral particles;(ii) a third nucleotide sequence encoding said viral polypeptide required for the assembly of the viral genome into viral particles, which third nucleotide sequence has a different nucleotide sequence to the second nucleotide sequence such that said third nucleotide sequence, or transcription product thereof, is resistant to cleavage directed by said gene product. The viral vector production system may be used to produce viral particles for use in treating or preventing viral infection.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.