Patent · US Expired

Diagnostics and therapy of diseases associated with HHV-8 infections

US6541253B2 · kind B2 · utility

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1References

1Claims

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Assignee

GSF-Forshungszentrum für Umwelt und Gesundheit, GmbH · DE

Inventors

Juergen Haas · Knittlingen, DE
Elisabeth Kremmer · Freising, DE
Stefanie Kliche · Berlin, DE

Key dates

Filing date	May 16, 2001
Grant date	Apr 1, 2003
Priority date	—
Expiry date	May 16, 2021

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2710/16422
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention is directed to monoclonal antibodies capable of specifically binding to and recognizing an antigenic determinant (epitope) of the protein kaposin or a derivative thereof, hybridoma cell lines producing said monoclonal antibodies, diagnostic systems for the detection of the presence of a kaposin protein or a derivative thereof as well as antibodies directed against the kaposin protein or a derivative thereof, methods for detection of the expression of kaposin protein or a derivative thereof in a biological sample, methods for the detection of antibodies directed against kaposin protein or a derivative thereof, uses of the monoclonal antibodies provided according to the invention and uses of the kaposin protein or a derivative thereof, each in diagnostics and therapy.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.