Mammalian IAP gene family, primers, probes and detection methods
US6541457B2 · kind B2 · utility
4Cited by
1References
18Claims
0Family size
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Key dates
| Filing date | Dec 1, 1998 |
| Grant date | Apr 1, 2003 |
| Priority date | — |
| Expiry date | Dec 1, 2018 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2510/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed is substantially pure DNA encoding mammalian IAP polypeptides; substantially pure polypeptides; and methods of using such DNA to express the IAP polypeptides in cells and animals to inhibit apoptosis. Also disclosed are conserved regions characteristic of the IAP-family and primers and probes for the identification and isolation of additional IAP genes. In addition, methods for treating diseases and disorders involving apoptosis are provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.