Fusion proteins comprising tumor necrosis factor receptor
US6541610B1 · kind B1 · utility
70Cited by
21References
30Claims
0Family size
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Inventor
Key dates
| Filing date | Mar 20, 1995 |
| Grant date | Apr 1, 2003 |
| Priority date | — |
| Expiry date | Mar 20, 2015 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Fusion proteins having a tumor necrosis factor receptor (TNF-R) polypeptide and at least one additional polypeptide covalently fused thereto and selected from an interleukin-1 receptor (IL-1R) and a second TNF-R polypeptide. The receptor polypeptides are preferably fused together by a peptidyl linker. Suitable fusions include, for example, TNF-R-linker-TNF-R; TNF-R-linker-IL-1R; and TNF-R-linker-TNF-R-linker-L-1R molecules.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.