Patent · US Expired

Methods of separating FTC isomers and derivatives thereof

US6541631B1 · kind B1 · utility

1Cited by
2References
17Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 26, 2000
Grant dateApr 1, 2003
Priority date
Expiry dateMay 26, 2020

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02P20/55
  • WIPO fieldChemical engineering
  • WIPO sectorChemistry

Abstract

The present invention relates to a method of preparing enantiomers and diastereomers of a 2′,3′-dideoxy-5-fluoro-3′thiocytadine (FTC) or a derivative thereof as represented by the following structural formula: In Structural Formula I, R is H, a substituted or unsubstituted organic acid radical, a substituted or unsubstituted alkyl group, a substituted or unsubstituted aryl group, a substituted or unsubstituted heteroaryl group, a substituted or unsubstituted aralkyl group, a substituted or unsubstituted heteroaralkyl group, a substituted or unsubstituted cycloalkyl group, a substituted or unsubstituted heterocycloalkyl group, a substituted or unsubstituted cycloalkylalkyl, a substituted or unsubstituted heterocycloalkylalkyl, a sugar or a protecting group.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.