Cell seeding of ceramic compositions
US6544290B1 · kind B1 · utility
29Cited by
55References
32Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 13, 1998 |
| Grant date | Apr 8, 2003 |
| Priority date | — |
| Expiry date | Feb 13, 2018 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S623/919
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a synthetic, poorly-crystalline apatitic (PCA) calcium phosphate material seeded with cells. Preferably, the cells are tissue-forming or tissue-degrading cells. The compositions provided by the present invention are useful for a variety of applications, including in vivo and in vitro tissue growth (preferably bone or cartilage), osseous augmentation, and methods of diagnosing disease states by assaying tissue-forming potential of cells isolated from a host. The invention also provides in vitro cell culture systems and cell encapsulation matrices.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.