Compositions comprising, as the main ingredient, allogenic activated-C4+ cells and method for producing and using the same
US6544514B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 8, 1999 |
| Grant date | Apr 8, 2003 |
| Priority date | — |
| Expiry date | May 22, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2501/515
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compositions or medicaments comprising allogenic activated-CD4+ cells as the main ingredient, which are attributable to an organ or bone marrow transplantation donor, have an extremely beneficial effect for preventing recidivation of a tumor and remedying various infections such as viral infections, and autoimmune diseases such as phagocytosis, without causing any serious GVHD. The allogenic activated-CD4+ cells can be produced by separating lymphocyte cells or CD4+ cells from peripheral blood of the donor or removing CD8+ cells from the peripheral blood of the donor by using anti-CD8+ antibodies to obtain CD4+ cells and proliferating the CD4+ cells thus prepared in proliferation activator.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.