Solid pharmaceutical compositions containing hexedecylphosphocholine (miltefosine) for oral administration in the treatment of leishmaniasis

US6544551B1 · kind B1 · utility

Assignee

• Zentaris GmbH · DE

Inventors

• Juergen Engel · Wiesendorf, DE
• Werner Sarlikiotis · Bielefeld, DE
• Thomas Klenner · Ingelheim am Rhein, DE
• Peter Hilgard · Frankfurt, DE
• Dieter Sauerbier · Altentreptow, DE
• Eckhard Milsmann · Bielefeld, DE

Key dates

• Filing date: Jul 24, 2000
• Grant date: Apr 8, 2003
• Expiry date: Jul 24, 2020

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to new solid pharmaceutical compositions containing hexadecylphosphocholine (miltefosine) for oral administration in the treatment of leishmaniasis, a process for the manufacture of said pharmaceutical composition, a dosage scheme for oral administration of said pharmaceutical composition in the treatment of leishmaniasis, and finally a combination comprising said solid pharmaceutical composition, antiemeticum, and/or an antidiarrhoeal.