Method of producing porous tablets with improved dissolution properties
US6544552B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 11, 2001 |
| Grant date | Apr 8, 2003 |
| Priority date | — |
| Expiry date | Jan 11, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/2095
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of producing a fast-dissolving pharmaceutical delivery device of moderate strength. The delivery device is a fully formed tablet composed of readily available sugars, strength polymers and a volatilizable excipient along with an active ingredient and optional flavorings. The tablet as made will disintegrate in an aqueous medium such as saliva in under 15 seconds, making mastication unnecessary or at least requiring only one or two bites on the tablet. Essential to the invention is the easily obtainable particle size ranges of the sugars and the volatilizable excipient which promotes optimum release and tablet strength. The invention also allows for effective taste masking of the active ingredient with standard particle coating techniques.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.