Methods and devices for the removal of psoralens from blood products
US6544727B1 · kind B1 · utility
99Cited by
36References
47Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jun 7, 1996 |
| Grant date | Apr 8, 2003 |
| Priority date | — |
| Expiry date | Jun 7, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M37/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods and devices for the removal of psoralens and psoralen photoproducts from blood products are described. The methods include contacting a psoralen- and irradiation-treated blood product with a resin capable of adsorbing psoralens and psoralen photoproducts. The removal process is particularly suitable for use with platelet concentrates and plasma because the process does not have a significant adverse effect on clotting factor function. The methods and devices can be incorporated with apheresis systems and other devices and procedures currently used to process blood products for transfusion.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.