Morphological mutants of filamentous fungi
US6544774B1 · kind B1 · utility
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3References
19Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 2, 2000 |
| Grant date | Apr 8, 2003 |
| Priority date | — |
| Expiry date | Jan 16, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12R2001/77
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to methods of obtaining a mutant cell from a filamentous fungal parent cell, comprising: (a) obtaining mutant cells of the parent cell; (b) identifying the mutant cell which exhibits a more restricted colonial phenotype and/or a more extensive hyphal branching than the parent cell; and (c) identifying the mutant cell which has an improved property for production of a heterologous polypeptide than the parent cell, when the mutant and parent cells are cultured under the same conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.