Synthesis of glycoconjugates of the globo-H epitope and uses thereof
US6544952B1 · kind B1 · utility
24Cited by
3References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 2, 1998 |
| Grant date | Apr 8, 2003 |
| Priority date | — |
| Expiry date | Feb 2, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K16/44
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a method of synthesizing a compound having the structure: as well as other related glycoconjugates useful as vaccines for inducing antibodies to epithelial cancer cells in an adjuvant therapy therefore, and in a method for preventing recurrence of epithelial cancer. The present invention also provides a vaccine comprising an amount of the compound described above effective to prevent the recurrence of cancer in a subject.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.