Mediators of hedgehog signaling pathways, compositions and uses related thereto
US6545005B1 · kind B1 · utility
127Cited by
1References
35Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 15, 2000 |
| Grant date | Apr 8, 2003 |
| Priority date | — |
| Expiry date | Sep 15, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention makes available methods and reagents for inhibiting aberrant growth states resulting from hedgehog gain-of-function by contacting the cell with a hedgehog antagonist, such as a small molecule, in a sufficient amount to aberrant growth state, e.g., to agonize a normal ptc pathway or antagonize hedgehog activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.