Aryl sulphonamide amino acid esters and analogues

US6545050B1 · kind B1 · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Joachim Mittendorf · Wuppertal, DE
• Jurgen Dressel · Radevormwald, DE
• Michael Matzke · Wuppertal, DE
• Jörg Keldenich · Wuppertal, DE
• Frank Mauler · Overath, DE
• Jean De Vry · Stolberg, DE
• Jürgen Franz · Haan, DE
• Peter Spreyer · Düsseldorf, DE
• Verena Vöhringer · Wuppertal, DE
• Joachim Schumacher · Wuppertal, DE
• Michael Harold Rock · Nørresundby, DK
• Ervin Horvath · Leverkusen, DE
• Arno Friedl · Bensberg, DE

Key dates

• Filing date: Feb 16, 2001
• Grant date: Apr 8, 2003
• Expiry date: Feb 16, 2021

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02P20/55
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to novel amino acid esters of arylsulphonamides and analogues, to processes for their preparation and to their use for the prophylaxis and treatment of neurodegenerative disorders, in particular for the treatment of cerebral apoplexy, craniocerebral trauma, pain and spasticity.