Microsphere containing glycidyl methacrylate covered polymer and spacer coupled compound for isolating substances
US6545132B1 · kind B1 · utility
2Cited by
2References
4Claims
0Family size
Inventors
Key dates
| Filing date | Nov 15, 1999 |
| Grant date | Apr 8, 2003 |
| Priority date | — |
| Expiry date | Nov 15, 2019 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/816
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A microsphere is prepared containing a compound possessing physiological activity coupled to a styrene-glycidyl methacrylate polymer through a spacer. Compounds that may be used include receptors such as proteins, and 3-[(5-(2,3-dimethoxy-6-methyl-benzoquinonyl)]-2-nonyl-2-propionic acid. A preferred spacer is an ethylene glycol diglycidyl ether derivative. Preferably, the whole surface of the styrene-glycidyl methacrylate polymer is covered with glycidyl methacrylate. The microsphere may be used for isolating and detecting substances such as proteins that bind to the coupled compound.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.