Molecular combing process for detecting macromolecules
US6548255B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 13, 2001 |
| Grant date | Apr 15, 2003 |
| Priority date | — |
| Expiry date | Jun 13, 2021 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/145555
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The subject of the present invention is a process for aligning a macromolecule (macromolecules) on the surface S of a support, characterized in that the triple line S/A/B (meniscus) resulting from the contact between a solvent A and the surface S and a medium B is caused to move on the said surface S, the said macromolecules having a part, especially an end, anchored on the surface S, the other part, especially the other end, being in solution in the solvent A.The subject of the present invention is also a process for detecting, measuring the intramolecular distance of, separating and/or assaying a macromolecule in a sample in which a process of alignment according to the invention is used.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.