Lymphoid tissue-specific cell production from hematopoietic progenitor cells in three-dimensional devices
US6548299B1 · kind B1 · utility
43Cited by
6References
36Claims
0Family size
Inventors
Key dates
| Filing date | May 18, 2000 |
| Grant date | Apr 15, 2003 |
| Priority date | — |
| Expiry date | May 18, 2020 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention relates to a method for lymphoid tissue-specific cell production from hematopoietic progenitor cells in unique, three-dimensional culture devices, in the presence of lymphoreticular stromal cells and in the absence of exogenously added growth factors. The resulting differentiated progeny. The lymphoid tissue-specific cells may be isolated at any sequential stage of differentiation and further expanded. The lymphoid tissue-specific cells also may be genetically altered at any stage of the process.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.