Patent · US Expired

Automated system and method for spectroscopic analysis

US6549861B1 · kind B1 · utility

76Cited by
130References
67Claims
0Family size

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Key dates

Filing dateAug 10, 2000
Grant dateApr 15, 2003
Priority date
Expiry dateMar 10, 2021

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01J2003/2866
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

An automated method for modeling spectral data is provided, wherein the spectral data generated by one of diffuse reflectance, clear transmission, or diffuse transmission. The method includes accessing a set of spectral data, the set of spectral data including, corresponding spectral data for each of a plurality of samples, the spectral data for each of the plurality of samples having associated therewith at least one constituent value, the at least one constituent value being a reference value for a target substance in the sample which is measured by a independent measurement technique. A plurality of data transforms are applied to the set of spectral data to generate, for each sample, a set of transformed and untransformed spectral data. The set of transformed and untransformed spectral data, with its associated constituent values, is divided into a calibration sub-set and a validation sub-set, and one or more of a partial least squares, a principal component regression, a neural net, or a multiple linear regression analysis is applied to the transformed and untransformed calibration data sub-sets to obtain corresponding modeling equations for predicting the amount of the target …

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