Treatment of Inflammatory bowel disease by inhibiting binding and/or signalling through &agr; 4 &bgr; 7 and its ligands and madcam
US6551593B1 · kind B1 · utility
39Cited by
13References
22Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 10, 1995 |
| Grant date | Apr 22, 2003 |
| Priority date | — |
| Expiry date | Feb 10, 2015 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/868
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to the treatment of individuals suffering from a disease associated with leukocyte recruitment to the gastrointestinal tract or other tissues as a result of binding of leukocytes to gut-associated endothelium expressing the molecule MAdCAM (such as inflammatory bowel disease), comprising administering to the individual an effective amount of an antibody which inhibits the binding of leukocytes to endothelial MAdCAM.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.