Antimicrobial agents
US6551998B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 22, 2000 |
| Grant date | Apr 22, 2003 |
| Priority date | — |
| Expiry date | Jun 22, 2020 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Antimicrobial compounds of formula I are disclosed:R1—X—R2whereinX is a group comprising of from about 4 to about 10 amino acids, wherein at least one of the amide (—CONH—) linkages is replaced by —CRaRaRbNRc—;Ra, Rb, and Rc are each independently hydrogen, (C1-C6)alkyl, (C2-C6)alkenyl, (C2-C6)alkynyl, (C3-C8)cycloalkyl, (C1-C6)alkoxycarbonyl, aryl, or heterocycle; andR1 and R2 are each independently hydrogen, a saccharide, a lipid, a solubilizing agent, or a suitable protecting group;or a pharmaceutically acceptable salt thereof, as well as pharmaceutical compositions comprising such compounds or salts, and methods of using such compounds or salts to treat a bacterial infection.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.