Materials and methods for the treatment of gastroesophageal reflux disease
US6552046B2 · kind B2 · utility
23Cited by
4References
33Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 7, 2001 |
| Grant date | Apr 22, 2003 |
| Priority date | — |
| Expiry date | Jun 7, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D211/46
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The subject invention provides novel compounds and compositions for the safe and effective treatment of gastroesophageal reflux and related conditions. In a preferred embodiment, the compositions of the subject invention comprise esterified cisapride derivatives. These compositions possess potent activity in treating gastroesophageal reflux disease and substantially reduce adverse effects associated with the administration of cisapride. These adverse effects include, but are not limited to, diarrhea, abdominal cramping and elevations of blood pressure and heart rate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.