3-ethyl-, 3-propyl- or 3-butyl-chroman and thiochroman derivatives
US6552068B1 · kind B1 · utility
1Cited by
5References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 13, 2002 |
| Grant date | Apr 22, 2003 |
| Priority date | — |
| Expiry date | Jun 13, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D311/58
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A compound having the following general formula (1): in whichR1 represents an ethyl group, etc.;R2 represents a hydrogen atom, etc.;R3 represents a C1-C5 perhalogenoalkyl group, etc.;each of R4 and R5 independently represents a hydrogen atom, etc.;X represents an oxygen atom or a sulfur atom;m represents an integer of 2 to 14; andn represents an integer of 2 to 7;or an enantiomer of the compound, or a hydrate or a pharmaceutically acceptable salt of the compound or its enantiomer is advantageous in pharmaceutical use because of its anti-estrogenic activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.