Process for the preparation of conjugates useful in the treatment of prostate cancer
US6552166B1 · kind B1 · utility
0Cited by
7References
35Claims
0Family size
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Key dates
| Filing date | Oct 18, 2000 |
| Grant date | Apr 22, 2003 |
| Priority date | — |
| Expiry date | Apr 6, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to the improved synthesis of compounds of formula I: which may be useful in the treatment of prostate cancer. Such compounds are synthesized in the presence of a carboxyl activating agent, an additive and a base for the preparation of a PSA conjugate which comprises an anthracycline antibiotic and an oligopeptide.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.