PEGylation reagents and compounds formed therewith
US6552170B1 · kind B1 · utility
58Cited by
58References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 14, 1994 |
| Grant date | Apr 22, 2003 |
| Priority date | — |
| Expiry date | Jun 14, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds are disclosed having the general formula R1-X-R2, wherein R1 and R2 are biologically active groups, at least one of which is polypeptidic. X is a non-peptidic polymeric group. R1 and R2 may be the same or different. Preferred R1 and R2 groups are TNF inhibitors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.