Use of background electrolytes to minimize flux variability during iontophoresis
US6553255B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 27, 2000 |
| Grant date | Apr 22, 2003 |
| Priority date | — |
| Expiry date | Oct 12, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N1/325
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A device and method are provided that minimize the changes in flux encountered during iontophoresis and reduce inter-subject variability. For drug delivery, the active agent to be delivered is administered in conjunction with at least one background ion having a hindrance factor that changes at a faster rate than the hindrance factor of the active agent when an electrical current is applied. For analyte extraction, the extraction reservoir contains at least one background ion having a hindrance factor that changes at a faster rate than the hindrance factor of the background ions of the analyte in the tissue when an electrical current is applied.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.