Sulfonamide lactam inhibitors of FXa and method
US6555542B1 · kind B1 · utility
8Cited by
12References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 29, 2002 |
| Grant date | Apr 29, 2003 |
| Priority date | — |
| Expiry date | Jan 29, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D491/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Sulfonamide lactams of the following formula wherein X, R1, R2, R3, R4, R4a, R5, R5a, R6, R6a, R7 and R8 are as described herein, are provided which inhibitors of Factor Xa and are useful as anticoagulants in the treatment of cardiovascular diseases associated with thromboses.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.