Use of &ggr;-tocopherol and its oxidative metabolite LLU-&agr; in the treatment of disease
US6555575B2 · kind B2 · utility
10Cited by
12References
3Claims
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Key dates
| Filing date | Apr 26, 2002 |
| Grant date | Apr 29, 2003 |
| Priority date | — |
| Expiry date | Apr 26, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is generally related to the discovery of the therapeutic benefit of administering &ggr;-tocopherol and &ggr;-tocopherol derivatives. More specifically, the use of &ggr;-tocopherol and racemic LLU-&agr;, (S)-LLU-&agr;, or &ggr;-tocopherol derivatives as antioxidants and nitrogen oxide scavengers which treat and prevent high blood pressure, thromboembolic disease, cardiovascular disease, cancer, natriuretic disease, the formation of neuropathological lesions, and a reduced immune system response are disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.