Patent · US Expired

Recombinant expression of insulin C-peptide

US6558924B1 · kind B1 · utility

3Cited by

3References

41Claims

0Family size

Assignee

Creative Peptides Sweden AB · SE

Inventors

Stefan Ståhl · Stockholm, SE
Mathias Uhlen · Uppsala, SE
Per Nygren · Helsingborg, SE
Per Jonasson · Stockholm, SE

Key dates

Filing date	Feb 7, 2000
Grant date	May 6, 2003
Priority date	—
Expiry date	Feb 7, 2020

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/75
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present invention provides a method of producing an insulin C-peptide, which comprises expressing in a host cell a multimeric polypeptide comprising multiple copies of the insulin C-peptide, and cleaving the expressed polypeptide to release single copies of the insulin C-peptide. Also provided are nucleic acid molecules, expression vectors and host cells, for use in such a method and the multimeric insulin C-peptide polypeptide expressed and cleaved in such a method.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.