Aminophenoxyacetic acid derivatives as neuroprotectants
US6559146B1 · kind B1 · utility
12Cited by
2References
25Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 1, 2000 |
| Grant date | May 6, 2003 |
| Priority date | — |
| Expiry date | Nov 1, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D401/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
There is provided an aminophenoxyacetic acid derivative of the following formula (I): wherein, R1, R2, R3 and R4 are, independent from each other, alkoxy group, alkyl group or aryl group, etc.; E1 and E2 are oxygen atom, sulfur atom, etc.; n is 0 to 5; X and Y are alkylene group, cycloalkylen group, or alkenylen group; Q is phenyl group which may be substituted or benzoyl group, etc,or a pharmaceutically acceptable salt thereof.These compounds have neuroprotective effects by inducing calbindin D28Kd, one of Ca2+-binding proteins.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.