Compounds and methods for regulating bacterial growth and pathogenesis

US6559176B1 · kind B1 · utility

Assignees

• THE TRUSTEES OF PRINCETON UNIVERSITY · US
• Quorex Pharmaceuticals, Inc. · US
• University Technologies International, Inc. · CA

Inventors

• Bonnie L. Bassler · Princeton, US
• Carol Dammel · Escondido, US
• Stephan Schauder · Val-de-Reuil, FR
• Kevan M. Shokat · San Francisco, US
• Jeffrey Michael Stein · Park Hills, US
• Michael G. Surette · Calgary, CA

Key dates

• Filing date: May 10, 2001
• Grant date: May 6, 2003
• Expiry date: May 10, 2021

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention provides autoinducer-2 analogs that regulate the activity of autoinducer-2 and methods of using such analogs for regulating bacterial growth and pathogenesis.